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Are angiotensin receptor blockersARBsan effective treatment for heart failureCochrane.
Congestive Heart FailureLisinopril is to be used in conjunction with a diuretic and where appropriate digitalisTherapy must be initiated under close medical supervisionusually in a hospitalBlood pressure and renal function should be monitoredboth before and during treatment with lisinoprilbecause severe hypotension andmore rarelyconsequent renal failure have been reportedsee WarningsHypotension and PrecautionsRenal Impairment
Agents Affecting Sympathetic ActivityAgents affecting sympathetic activitye.gganglionic blocking agents or adrenergic neuron blocking agentsmay be used with cautionBeta-adrenergic blocking drugs add some further antihypertensive effect to lisinopril.
The recommended initial dose is 2.5 mg/dayIf requiredthe dose should be increased graduallydepending on the patient responseThe usual effective dosage range is 5 to 20 mg/day administered in a single daily doseDose titration may be performed over a 2 to 4 week periodor more rapidly if indicated by the presence of residual signs and symptoms of heart failure.
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