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A cymbalta duloxetine is an antidepressant classified as a serotonin and norepinephrine reuptake inhibitor snri used to treat depression, anxiety, and pain from fibromyalgia.

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Ask your doctor before taking a nonsteroidal anti-inflammatory drugNSAIDfor painarthritisfeveror swellingThis includes aspirinibuprofenAdvilMotrinnaproxenAlevecelecoxibCelebrexdiclofenacindomethacinmeloxicamand othersUsing an NSAID with Cymbalta may cause you to bruise or bleed easily.

Nauseaupper stomach painitchingloss of appetitedark urineclay-colored stoolsjaundiceyellowing of the skin or eyesfeeling like you might pass outagitationhallucinationsfeverfast heart rateoveractive reflexesvomitingdiarrhealoss of coordinationvery stiffrigidmuscleshigh feversweatingconfusiontremorseasy bruisingunusual bleedingpainful or difficult urinationheadachetrouble concentratingmemory problemsweaknessfeeling unsteadyseizureshallow breathing or breathing that stopsor severe skin reaction feversore throatswelling in your face or tongueburning in your eyesskin painfollowed by a red or purple skin rash that spreadsespecially in the face or upper bodyand causes blistering and peeling.

40-60 mg/day PO initiallyin single daily dose or divided q12hr for 1 week if patient needs to adjust to therapy)

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if you wish or need to stop taking cymbalta, your doctor will tell you how to reduce your dose gradually over time.