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QuinidineAlthough not studied in vitro or in vivoconcomitant administration of fluconazole with quinidine may result in inhibition of quinidine metabolismUse of quinidine has been associated with QT prolongation and rare occurrences of torsades de pointesCoadministration of fluconazole and quinidine is contraindicatedsee section 4.3
Safety and efficacy for genital candidiasis indication in paediatric population has not been establishedCurrent available safety data for other paediatric indications are described in section 4.8If treatment for genital candidiasis is imperative in adolescentsfrom 12 to 17 years oldthe posology should be the same as adults posology.
Older adults may be more sensitive to the side effects of this drugespecially rashvomitingdiarrheaand QT prolongationsee above
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sixteen percent of over 4000 patients treated with diflucan fluconazole in clinical trials of 7 days or more experienced adverse events.