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Call your healthcare provider for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.

Using Prograf may also increase your risk of developing skin cancerespecially if you are treated over long periods of time with drugs that weaken the immune systemTalk with your doctor about your specific risk.

The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongationBefore using tacrolimustell your doctor or pharmacist of all the drugs you take and if you have any of the following conditionscertain heart problemsheart failureslow heartbeatQT prolongation in the EKGfamily history of certain heart problemsQT prolongation in the EKGsudden cardiac death

Tacrolimus can pass into breast milk and may harm a nursing babyYou should not breast-feed while you are using Prograf.

Shakingheadachediarrheanausea/vomitingupset stomachloss of appetitetrouble sleepingand tingling of the hands/feet may occurIf any of these effects persist or worsentell your doctor or pharmacist promptly.

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prograf is an extended-release capsule and is not the same as prograf immediate-release capsules.